Luxendo is a recent spin-off from EMBL in Heidelberg, commercializing advanced Single Plane Illumination Microscopes (SPIM). Compared to modern state of the art confocal or wide-field microscopes, SPIM technology allows for significantly reduced sampling times at comparable and even higher resolution with highly reduced damaging side effects on the living objects investigated. Nature Science has characterized SPIM technology, also known as light sheet microscopy, as “Method of the Year 2014”. Please visit www.luxendo.eu for more information.